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VER-49009

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SI-5757

VER-49009, >98% (HPLC)

CAS No. : [558640-51-0]

MDL No. : MFCD18382094

Synonyms : CCT 129397

IUPAC Name : 3-(5-Chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide

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Chemical Properites
Mol. Formula :
C19H18ClN3O4
Mol. Weight :
387.82
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : VER-49009 is a Hsp90 inhibitor, with an IC50 of 25 nM and a Kd of 78 nM.

References : Dymock B. W. et al.: J. Med Chem., 48(13), 4212-5, 2005; Sharp S. Y. et al.: Mol Cancer Ther., 6(4), 1198-211, 2007; Sun X. et al.: Mol Cell Biochem., 330(1-2), 181-5,2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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