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Vilanterol impurity 1

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Vilanterol impurity 1, >98%

CAS No. : [2677047-63-9]

IUPAC Name : (R)-2-((6-(2-((2,6-Dichlorobenzyl)oxy)ethoxy)hexyl)amino)-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethan-1-ol 2,2,2-triphenylacetate

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Chemical Properites
Mol. Formula :
C27H37Cl2NO5 C20H16O2
Mol. Weight :
814.84
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Vilanterol, which is a selective long-acting β2 adrenoreceptor agonist (LABA). Vilanterol is used for the treatment of chronic obstructive pulmonary disease (COPD) and asthma.

References : Slack R. J. et al.: J. Pharmacol Exp Ther., 344(1), 218-230, 2013. Calzetta L. et al.: Eur. J. Pharmacol., Jul 14, S0014-2999(17), 30470-3, 2017; Kempsford R. et al.: Pulm Pharmacol Ther., 26(2), 256-264; 2013; Harrell A. W. et al.: Drug Metab Dispos., 41(1), 89-100, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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