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Vildagliptin carboxylic acid methyl ester

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SL-4243

Vildagliptin carboxylic acid methyl ester, >98%

CAS No. : [948574-56-9]

IUPAC Name : (S)-Methyl 1-(2-((3-hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carboxylate

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Chemical Properites
Mol. Formula :
C18H28N2O4
Mol. Weight :
336.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Vildagliptin, which is an inhibitor of dipeptidyl peptidase-4 (DPP-4) class of drugs. A new oral antidiabetic agent that enhances pancreatic islet cell responsiveness to glucose.

References : Villhauer E. B. et al.: J. Med. Chem., 46(13), 2774-2789, 2003; Duttaroy A. et al.: Eur. J. Pharmacol., 650(2-3), 703-707, 2011; Jin H. Y. et al.: Arch Med Res., 40(7), 536-544, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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