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Vildagliptin β-D-glucuronide

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SL-4245

Vildagliptin β-D-glucuronide, >98%

CAS No. : [1147403-03-9]

Synonyms : Vildagliptin O-glucuronide

IUPAC Name : (2S,3S,4S,5R,6S)-6-(((1R,3S,5R,7S)-3-((2-((S)-2-Cyanopyrrolidin-1-yl)-2-oxoethyl)amino)adamantan-1-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

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Chemical Properites
Mol. Formula :
C23H33N3O8
Mol. Weight :
479.52
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Vildagliptin β-D-glucuronide is a glucoronide metabolite of Vildagliptin, which is an inhibitor of dipeptidyl peptidase-4 (DPP-4) class of drugs. A new oral antidiabetic agent that enhances pancreatic islet cell responsiveness to glucose.

References : Villhauer E. B. et al.: J. Med. Chem., 46(13), 2774-2789, 2003; Duttaroy A. et al.: Eur. J. Pharmacol., 650(2-3), 703-707, 2011; Jin H. Y. et al.: Arch Med Res., 40(7), 536-544, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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