Vismodegib

SI-4591

Vismodegib, >98% (HPLC)

CAS No. : [879085-55-9]

MDL No. : MFCD12407408

Synonyms : GDC-0449

IUPAC Name : 2-Chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	135.00		Back Order	Estimated to ship on 20 September 2026
5G	495.00		Back Order	Estimated to ship on 20 September 2026
10G	955.00		Back Order	Estimated to ship on 20 September 2026
25G	1895.00		Back Order	Estimated to ship on 20 September 2026

Applications : Vismodegib is a potent, novel and specific hedgehog inhibitor with IC₅₀ of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.

References : Scales S. J. et al.: Trends Pharmacol Sci., 30(6), 303-312, 2009; Zhang Y. et al.: Neoplasia 11(1), 96-101,2009; Tian F. et al.: Anticancer Res., 32(1), 89-94, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.