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CAS No. : [2172652-48-9]
Synonyms : RMC-4630; SHP2-IN-7
IUPAC Name : (6-((2-Amino-3-chloropyridin-4-yl)thio)-3-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-5-methylpyrazin-2-yl)methanol
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C20H27ClN6O2S | Mol. Weight : 450.99 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Vociprotafib functions as an orally active and selective SHP2 inhibitor that effectively blocks RAS–RAF–MEK–ERK signaling. It demonstrates robust antitumor efficacy, markedly accelerating and amplifying tumor regression in Osimertinib‑sensitive EGFR‑mutant mouse models.
References : Ou. S. I. et al.: Journal of Thoracic Oncology, 15(2), S15-S16, 2020; Smith J. A. et al.: Cancer Research, 80(16), 1943-1943, 2020.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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