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SI-6094

Volixibat, >98% (HPLC)

CAS No. : [1025216-57-2]

Synonyms : SHP-626; LUM-002

IUPAC Name : ((2R,3R,4S,5R,6R)-4-(Benzyloxy)-6-(3-(3-((3S,4R,5R)-3-butyl-7-(dimethylamino)-3-ethyl-4-hydroxy-1,1-dioxido-2,3,4,5-tetrahydrobenzo[b]thiepin-5-yl)phenyl)ureido)-3,5-dihydroxytetrahydro-2H-pyran-2-yl)methyl hydrogen sulfate

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Chemical Properites
Mol. Formula :
C38H51N3O12S2
Mol. Weight :
805.96
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Volixibat competitively inhibits ASBT with high selectivity and minimal systemic absorption, enhancing fecal bile‑acid excretion. These properties make it a valuable tool for studying bile‑acid modulation in NASH and related metabolic diseases.

References : Salic K. et al.: PLoS One, 14(6), e0218459, 2019; Palmer M. et al.: BMC Pharmacol. Toxicol., 19(1), 10. 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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