Vonoprazan metabolite M-III

SL-9181

Vonoprazan metabolite M-III, >98%

CAS No. : [1883595-39-8]

IUPAC Name : (E)-1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanimine oxide

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Applications : This is a metabolite of Vonoprazan, which is an orally active potassium-competitive acid blocker that inhibits H+, K+-ATPase activity. Vonoprazan is used to treat erosive esophagitis and heartburn.

References : Flick C. A. et al.: Bioorg. Med. Chem. 24(9), 1937-1980, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.