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Vopimetostat

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SI-8107

Vopimetostat, >98% (HPLC)

CAS No. : [2760483-96-1]

Synonyms : TNG-462

IUPAC Name : N-(6-Amino-5-ethylpyridin-3-yl)-2-((2R,5S)-5-methyl-2-(2-(1-methylpiperidin-4-yl)benzo[d]thiazol-5-yl)piperidin-1-yl)-2-oxoacetamide

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Chemical Properites
Mol. Formula :
C28H36N6O2S
Mol. Weight :
520.7
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Vopimetostat is an orally active PRMT5 inhibitor that selectively targets cancers with MTAP loss or elevated MTA levels. Its MTAP‑synergistic mechanism drives robust antitumor effects, making it valuable for studying PRMT5‑dependent tumor biology.

References : Briggs K. et al.: J. Cancer Research, 83(7 Supplement), 4970-4970, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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