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Voxelotor

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SI-6273

Voxelotor, >98% (HPLC)

CAS No. : [1446321-46-5]

Synonyms : GBT-440

IUPAC Name : 2-Hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C19H19N3O3
Mol. Weight :
337.38
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Voxelotor effectively inhibits HbS polymerization, thereby limiting red blood cell sickling and improving hemoglobin function. These properties highlight its relevance for mechanistic and therapeutic studies in sickle cell disease.

References : Oksenberg D. et al.: Br. J. Haematol., 175(1), 141-53, 2016; Metcalf B. et al.: ACS Med. Chem. Lett., 8(3), 321-326, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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