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Voxelotor-d6

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SI-6274

Voxelotor-d6, >98% (HPLC)

CAS No. : [2170187-39-8]

Synonyms : GBT-440-d6

IUPAC Name : 2-Hydroxy-6-((2-(1-(propan-2-yl-1,1,1,3,3,3-d6)-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C19H13D6N3O3
Mol. Weight :
343.42
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Voxelotor‑d6 is the deuterated analog of Voxelotor and retains its potent HbS polymerization‑inhibitory activity. It is useful for tracer, metabolic, and PK studies in the context of sickle cell disease research.

References : Russak E. M. et al.: Ann. Pharmacother., 53(2), 211-216, 2019; Oksenberg D. et al.: Br. J. Haematol., 175(1), 141-53, 2016; Metcalf B. et al.: ACS Med. Chem. Lett., 8(3), 321-326, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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