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Voxtalisib

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SI-5341

Voxtalisib, >98% (HPLC)

CAS No. : [934493-76-2]

MDL No. : MFCD18252649

Synonyms : SAR245409; XL765

IUPAC Name : 2-Amino-8-ethyl-4-methyl-6-(1H-pyrazol-5-yl)pyrido[2,3-d]pyrimidin-7(8H)-one

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100MG500.00
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Chemical Properites
Mol. Formula :
C13H14N6O
Mol. Weight :
270.30
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Voxtalisib is a dual inhibitor of mTOR/PI3K with antiproliferative, antiangiogenic, and proapoptotic activities.

References : Garcia-Echeverria C. et al.: Oncogene 27(41), 5511-5526, 2008; Mirzoeva O. K. et al.: J. Mol. Med., 89(9), 877-889,2011; Prasad G. et al.: Neuro Oncol., 13(4), 384-392, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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