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Vps34-IN-3

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SI-7146

Vps34-IN-3, >98% (HPLC)

CAS No. : [2770104-92-0]

IUPAC Name : (5aS,8aR)-2-((R)-3-Methylmorpholino)-5,5a,6,7,8,8a-hexahydro-4H-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one

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Chemical Properites
Mol. Formula :
C14H20N4O2
Mol. Weight :
276.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a potent, selective, and orally bioavailable VPS34 kinase inhibitor that effectively blocks PI3KC3/VPS34‑dependent signaling. It is suitable for studies involving autophagy regulation, endosomal trafficking, lipid kinase biology, and VPS34‑driven disease mechanisms.

References : Hu X. D. et al.: J. Med. Chem., 65(17), 11500-11512, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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