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VU-0424238

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SI-1278

VU-0424238, >98% (HPLC)

CAS No. : [1396337-04-4]

MDL No. : MFCD28386341

Synonyms : Auglurant; VU0424238

IUPAC Name : N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG355.00
Back Order  Estimated to ship on 04 October 2026
10MG555.00
Back Order  Estimated to ship on 04 October 2026
25MG855.00
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50MG1655.00
Back Order  Estimated to ship on 04 October 2026
100MG2655.00
Back Order  Estimated to ship on 04 October 2026
250MG4655.00
Back Order  Estimated to ship on 04 October 2026
500MG8655.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C16H12FN5O2
Mol. Weight :
325.30
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : VU-0424238 is a potent, selective, orally active mGlu5 negative allosteric modulator with Ki of 4.4 nM, displays >900-fold selectivity for mGlu5 versus the other mGlu receptors.

References : Felts S. A. et al.: J. Med. Chem., 60(12), 5072-5085, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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