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VU-6001376

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SI-2195

VU-6001376, >98% (HPLC)

CAS No. : [1968546-34-0]

IUPAC Name : 6-((1H-Pyrazolo[4,3-b]pyridin-3-yl)amino)-N-(3,3-difluorocyclobutyl)benzo[d]isothiazole-3-carboxamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Note: VU-6001376 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C18H14F2N6OS
Mol. Weight :
400.41
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : VU-6001376 is a potent, selective, positive allosteric modulator of mGlu4 with EC50 of 28 nM, 49% Glu Max, shows no activity against other 7 mGlu receptors.

References : Bollinger R. S. et al.: J. Med. Chem., 62(1), 342-358, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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