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WCK-5153

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SI-5753

WCK-5153, >98% (HPLC)

CAS No. : [1452460-79-5]

IUPAC Name : (2S,5R)-7-Oxo-2-(2-((S)-pyrrolidin-3-yl)hydrazine-1-carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate

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Back Order  Estimated to ship on 04 October 2026
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We accept
Note: WCK 4234 sodium is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us atsales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C11H19N5O6S
Mol. Weight :
349.36
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : WCK-5153 is a novel inhibitor of PBP2 showing potent "β-lactam enhancer" activity against Pseudomonas aeruginosa, Including multidrug-resistant metallo-β-lactamase-producing high-risk clones. WCK 5153 demonstrated specific high-affinity binding to PBP2 of A. baumannii. WCK 5153 shows a potent β-lactam enhancer effect against A. baumannii, including a multidrug-resistant OXA-23-producing ST2 international clone.

References : Papp-Wallace K. M. et al.: J. Med. Chem., 61(9), 4067-4086, 2018; Moya B. et al.: Antimicrob Agents Chemother., 61(11), pii: e01238-17, 2017; Moya B. et al.: Antimicrob Agents Chemother., 61(6), pii: e02529-16, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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