WDR5-IN-5

SI-7038

WDR5-IN-5, >98% (HPLC)

CAS No. : [2417012-26-9]

IUPAC Name : (R)-7-((1H-Imidazol-1-yl)methyl)-2-(cyclopropyl(4-methylpyridin-2-yl)methyl)-5-(1-ethyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : WDR5‑IN‑5 is an orally active and selective inhibitor of the WIN site of WD repeat domain 5 (WDR5). It exhibits strong anti‑proliferative activity in cancer cells and demonstrates a favorable pharmacokinetic profile in mice. WDR5‑IN‑5 binds WDR5 with exceptionally high affinity, with a K_i value below 0.02 nM, supporting its potential as a powerful chemical probe and a promising lead for further therapeutic development.

References : Teuscher B. K. et al.: J. Med. Chem., 65(8), 6287-6312, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.