WP-1066

SI-6711

WP-1066, >98% (HPLC)

CAS No. : [857064-38-1]

IUPAC Name : (S,E)-3-(6-Bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : WP-1066 inhibits JAK2/STAT3 signaling and also affects STAT5 and ERK1/2 without impacting JAK1 or JAK3. Its ability to cross the blood–brain barrier makes it suitable for studies involving intracranial tumors and CNS‑associated inflammatory pathways.

References : Verstovsek S. et al.: Clin. Cancer Res., (3), 788-796, 2008; Hatiboglu M. A. et al.: Int. J. Cancer., 131(1), 8-17, 2012; Ferrajoli A. et al.: Cancer Res., 67(23), 11291-11299, 2007; Kong L. Y. et al.: Clinical cancer research: an official journal of the American Association for Cancer Research, 14(18), 5759, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.