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CAS No. : [232935-92-1]
Synonyms : RO-914714
IUPAC Name : (Z)-4-(2-((3H-Indol-3-ylidene)methyl)hydrazineyl)-6-morpholino-N-phenyl-1,3,5-triazin-2-amine
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C22H22N8O | Mol. Weight : 414.47 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : WX-8 potently inhibits PIKFYVE (K_d = 0.9 nM) with weaker activity toward PIP4K2C (340 nM). It disrupts lysosomal fission without altering homotypic lysosomal fusion and is used to investigate lysosomal and autophagy‑regulated mechanisms in cancer models.
References : Roy A. et al.: Cells, 13(13), 1096, 2024; Sharma G. et al: Autophagy, 15(10), 1694-1718, 2019.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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