WZ-4002

SI-2482

WZ-4002, >98% (HPLC)

CAS No. : [1213269-23-8]

MDL No. : MFCD16621244

IUPAC Name : N-(3-((5-Chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)acrylamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
10MG	75.00		Back Order	Estimated to ship on 04 October 2026
25MG	155.00		Back Order	Estimated to ship on 04 October 2026
50MG	225.00		Back Order	Estimated to ship on 04 October 2026
100MG	395.00		Back Order	Estimated to ship on 04 October 2026
250MG	695.00		Back Order	Estimated to ship on 04 October 2026
500MG	1195.00		Back Order	Estimated to ship on 04 October 2026

Applications : WZ4002 is a potent, mutant-selective, covalent EGFR inhibitor with IC₅₀ of 2, 8, 3 and 2 nM for EGFR ^L858R, EGFR ^L858R/T790M, EGFR ^E746-A750 and EGFR^{E746-A750/T790M} respectively.

References : Zhou W. et al.: Nature 462(7276), 1070-1074,2009; Sakuma Y. et al.: Lab Invest., 92(3), 371-383, 2012; Zannetti A. et al.: J. Nucl Med., 53(3), 443-450, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.