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Xevinapant

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SI-5081

Xevinapant, >98% (HPLC)

CAS No. : [1071992-99-8]

MDL No. : MFCD22124467

Synonyms : Debiopham; Debio-1143; AT-406; SM-406

IUPAC Name : (5S,8S,10aR)-N-Benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide

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Chemical Properites
Mol. Formula :
C32H43N5O4
Mol. Weight :
561.73
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Xevinapant is a potent and orally bioavailable Smac mimetic and an antagonist of IAPs. Xevinapant is in clinical development for the potential treatment of cancer.

References : Cai Q. et al.: J. Med Chem., 54(8), 2714-2726, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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