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SI-5760

XL888, >98% (HPLC)

CAS No. : [1149705-71-4]

MDL No. : MFCD26142606

IUPAC Name : 5-(((R)-sec-Butyl)amino)-N1-(8-(5-(cyclopropanecarbonyl)pyridin-2-yl)-8-azabicyclo[3.2.1]octan-3-yl)-2-methylterephthalamide

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10MGRequest A Quote
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Chemical Properites
Mol. Formula :
C29H37N5O3
Mol. Weight :
503.65
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : XL888 is a heat shock protein-90 (Hsp90) inhibitor, with an IC50 of 24 nM.

References : Haarberg H. E. et al.: Mol Cancer Ther., 12(6), 901-12, 2013; Paraiso K. H. et al.: Clin Cancer Res., 18(9), 2502-14, 2012; Bussenius J. et al.: Bioorg Med Chem Lett., 22(17), 5396-404, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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