XY-153

SI-7329

XY-153, >98% (HPLC)

CAS No. : [2933176-32-8]

IUPAC Name : 2-(2-Cyclopentyl-1H-imidazol-5-yl)-7-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-5-methylfuro[3,2-c]pyridin-4(5H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : XY-153 preferentially targets the BD2 domains of BET proteins, displaying sub‑nanomolar potency for BRD4‑BD2 and low‑nanomolar activity for BRD3‑BD2 and BRD2‑BD2. It demonstrates strong antiproliferative activity and is valuable for investigating BD2‑dependent transcriptional regulation in AML and broader cancer models.

References : Li J. et al.: J. Med. Chem., 65(7), 5760-5799, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.