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Y-33075

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SI-6300

Y-33075, >98% (HPLC)

CAS No. : [199433-58-4]

Synonyms : Y-39983 free base

IUPAC Name : (R)-4-(1-Aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide

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Chemical Properites
Mol. Formula :
C16H16N4O
Mol. Weight :
280.33
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Y‑33075 is a selective and highly potent ROCK inhibitor engineered from Y‑27632, achieving an IC50 of 3.6 nM. Its increased potency supports applications requiring robust ROCK pathway suppression.

References : Tokushige H. et al.: Ophthalmol., 48(7), 3216-3222, 2007; Tokushige H. et al.: Curr. Eye Res., 36(10), 964-70, 2011; Watabe H. et al.: Jpn. J. Ophthalmol., 55(4), 411-7, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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