YH-53

SI-7125

YH-53, >98% (HPLC)

CAS No. : [1471484-62-4]

IUPAC Name : N-((S)-1-(((S)-1-(benzo[d]thiazol-2-yl)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)-4-methoxy-1H-indole-2-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : YH‑53 potently inhibits SARS‑CoV‑1 and SARS‑CoV‑2 3CL^pro with low‑nanomolar K_i values and contains a unique benzothiazolyl ketone within its peptidomimetic structure. It strongly blocks SARS‑CoV‑2 replication, highlighting its relevance for COVID‑19 studies.

References : Sho K. et al.: J. Med. Chem., 65(4), 2926-2939, 2022; Pillaiyar T. et al.: Eur. J. Med. Chem., 68, 372-84, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.