YKL-05-099

SI-7503

YKL-05-099, >98% (HPLC)

CAS No. : [1936529-65-5]

IUPAC Name : 3-(2-Chloro-6-methylphenyl)-7-((2-methoxy-4-(1-methylpiperidin-4-yl)phenyl)amino)-1-(5-methoxypyridin-2-yl)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : YKL‑05‑099 selectively inhibits SIK1 and SIK3 with low‑nanomolar potency and displays slightly weaker activity against SIK2. Its balanced SIK‑family profile makes it a valuable tool for studying SIK‑dependent signaling in metabolic and inflammatory biology.

References : Sundberg T. B. et al.: ACS Chem. Biol., 11(8), 2105-11, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.