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YLT-11

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SI-8027

YLT-11, >98% (HPLC)

CAS No. : [3040940-49-3]

IUPAC Name : (E)-N-(4-(3-(4-((Dimethylamino)methyl)styryl)-1H-indazol-6-yl)pyrimidin-2-yl)acetamide

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C24H24N6O
Mol. Weight :
412.5
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : YLT‑11 selectively targets PLK4 with nanomolar affinity (Kd = 5.2 nM) and minimal activity on PLK1 and PLK3. It exhibits antiproliferative effects, promotes apoptosis, and induces G2/M arrest, supporting its relevance in PLK4‑dependent cancer research.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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