YLT-11

SI-8079

YLT-11, >98% (HPLC)

CAS No. : [3040940-49-3]

IUPAC Name : (E)-N-(4-(3-(4-((Dimethylamino)methyl)styryl)-1H-indazol-6-yl)pyrimidin-2-yl)acetamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : YLT‑11 is an orally active PLK4 inhibitor with marked selectivity, showing sub‑10 nM binding to PLK4 (Kd = 5.2 nM) while sparing PLK1, PLK2, and PLK3. It exhibits antiproliferative effects, promotes apoptosis, and causes G2/M cell‑cycle arrest, highlighting its relevance in anticancer research.

References : Lei Q. et al.: Cell Death Dis., 9(11), 1066, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.