YM-58483

SI-6870

YM-58483, >98% (HPLC)

CAS No. : [223499-30-7]

Synonyms : BTP2

IUPAC Name : N-(4-(3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : YM‑58483 potently and selectively inhibits CRAC channel activity, blocking Ca²⁺ entry and downstream signaling. YM‑584832 also suppresses SOCE, making these molecules valuable probes for studying Ca²⁺‑dependent immune responses and cellular activation.

References : Qi Z. et al.: Cell Mol. Neurobiol., 36(7), 1035-43, 2016; Ohga K. et al.: Int Immunopharmacol., 8(13-14), 1787-9, 2008; Ohga K. et al.: Pulm Pharmacol Ther., 21(2), 360-9, 2008; Yoshino T. et al.: Eur J Pharmacol., 560(2-3), 225-33, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.