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SI-7415

Z-11, >98% (HPLC)

CAS No. : [2737262-24-5]

Synonyms : CDK9 inhibitor

IUPAC Name : 14,25-Difluoro-N-(2-morpholinoethyl)-5,12-dioxa-3-aza-2(4,2)-pyrimidina-1,4(1,3)-dibenzenacyclododecaphane-44-carboxamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C29H33F2N5O4
Mol. Weight :
553.61
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This selectively inhibits CDK9 with low‑nanomolar potency (IC50 = 3.20 nM). It effectively suppresses cellular proliferation and promotes apoptosis, making it a valuable tool for probing transcriptional regulation and CDK9‑mediated cancer biology.

References : Wu T. et al.: J. Med. Chem., 66(22), 15340-15361, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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