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(Z)-Olopatadine isopropyl ester trifluoro acetate

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(Z)-Olopatadine isopropyl ester trifluoro acetate, >98%

Related CAS No. : [1206456-44-1] of the free base compound

IUPAC Name : Isopropyl (Z)-2-(11-(3-(dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetate 2,2,2-trifluoroacetate

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Chemical Properites
Mol. Formula :
C24H29NO3 . CF3CO2H
Mol. Weight :
493.52
Appearance :
Off-white solid (hygroscopic)
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an analog of Olopatadine, which is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis.

References : Kam K. W. et al.: Ocul Immunol Inflamm., 25(5), 663-677, 2017; Leonardi A. et al.: Expert Opin Pharmacother., 11(6), 969-81, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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