Zabedosertib

SI-6345

Zabedosertib, >98% (HPLC)

CAS No. : [1931994-81-8]

Synonyms : BAY-1834845

IUPAC Name : N-(6-(2-Hydroxypropan-2-yl)-2-(2-(methylsulfonyl)ethyl)-2H-indazol-5-yl)-6-(trifluoromethyl)picolinamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Zabedosertib is a selective, orally active IRAK4 inhibitor with low‑nanomolar potency. It blocks TLR‑dependent innate immune signaling and reduces inflammation triggered by IL‑1β, LPS, and imiquimod, making it valuable for studying IRAK4‑mediated inflammatory pathways.

References : Li Q. et al.: Biomed. Pharmacother., 153, 113459, 2022; Bothe U. et al.: J. Med. Chem., 67(2), 1225-1242, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.