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ZB-R-55

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SI-8006

ZB-R-55, >98% (HPLC)

CAS No. : [2416593-55-8]

IUPAC Name : (S)-3-Benzyl-N-(7-(cyclopropylethynyl)-5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-1H-1,2,4-triazole-5-carboxamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C25H23N5O3
Mol. Weight :
441.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ZB‑R‑55 potently inhibits RIPK1 through a dual‑mode mechanism involving simultaneous occupancy of the allosteric and ATP‑binding sites. It blocks necroptosis in cancer cells and is suitable for investigating RIPK1‑driven inflammatory pathologies, including SIRS and sepsis.

References : Yang X. et al.: Angew.Chem. Int. Ed. Engl., 61(5), e202114922, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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