Zedoresertib

SI-6772

Zedoresertib, >98% (HPLC)

CAS No. : [2243882-74-6]

Synonyms : Debio-0123; WEE1-IN-5

IUPAC Name : 3-(2,6-Dichlorophenyl)-1-methyl-7-((3-methyl-4-(1-methylpiperidin-4-yl)phenyl)amino)-2,3-dihydropyrimido[4,5-d]pyrimidin-4(1H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Zedoresertib potently inhibits WEE1 (IC₅₀ = 0.8 nM), leading to reduced phospho‑CDC2 levels and G₂‑checkpoint abrogation. This checkpoint override sensitizes cancer cells to DNA damage, making it a valuable tool for studying WEE1‑targeted anticancer strategies.

References : Gelderblom H. et al.: Ann. Oncol., 31, S501-S502, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.