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Zelatriazin

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SI-6754

Zelatriazin, >98% (HPLC)

CAS No. : [1929519-13-0]

Synonyms : TAK-041; NBI-1065846

IUPAC Name : (S)-2-(4-Oxobenzo[d][1,2,3]triazin-3(4H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide

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Chemical Properites
Mol. Formula :
C18H15F3N4O3
Mol. Weight :
392.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Zelatriazin activates GPR139 with nanomolar potency (EC50 = 22 nM) and exhibits high receptor selectivity. It is a valuable tool compound for investigating mechanisms underlying the negative symptoms of schizophrenia.

References : Reichard H. A. et al.: J. Med. Chem., 10, 1021/acs.jmedchem.1c00820, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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