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Ziprasidone EP impurity E

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SL-5039

Ziprasidone EP impurity E, >98%

CAS No. : [1159977-04-4]

Synonyms : Ziprasidone USP related compound D

IUPAC Name : 3-(1,2-Benzisothiazol-3-yl)-5-[2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one

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Chemical Properites
Mol. Formula :
C28H24ClN5OS2
Mol. Weight :
546.1
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Ziprasidone (Ziprasidone EP impurity E), which is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.

References : Schmidt A. W. et al.: Eur J. Pharmacol, 425(3), 197-201, 2001; Su Z. et al:. Biochem Pharmacol, 71(3), 278-286, 2006; Kirk S. L. et al. Eur. J. Pharmacol, 505(1-3), 253-254, 2004; Terry A. V. Jr. et al.: J. Pharmacol Exp Ther, 318(2), 709-724, 2006; Sprouse J. S. et al.: Neuropsychopharmacology, 21(5), 622-631, 1999.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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