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SI-1181

Ziritaxestat, >98% (HPLC)

CAS No. : [1628260-79-6]

MDL No. : MFCD31544330

Synonyms : GLPG-1690

IUPAC Name : 2-((2-Ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile

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Chemical Properites
Mol. Formula :
C30H33FN8O2S
Mol. Weight :
588.70
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GLPG-1690 is a first-in-class, potent, competitive autotaxin inhibitor with Ki/IC50 of 15 nM/131 nM.

References : Desroy N. et al.: J. Med. Chem., 60(9), 3580-3590, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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