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ZL-0454

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SI-7060

ZL-0454, >98% (HPLC)

CAS No. : [2229042-77-5]

IUPAC Name : (E)-4-((2-Amino-4-hydroxy-5-methylphenyl)diazenyl)-N-cyclopentylbenzenesulfonamide

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Chemical Properites
Mol. Formula :
C18H22N4O3S
Mol. Weight :
374.46
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ZL-0454 selectively targets BRD4, inhibiting the BD1 and BD2 bromodomains with IC50 values of 49 nM and 32 nM, respectively. Its potency makes it a valuable tool for probing BRD4‑dependent epigenetic and transcriptional regulation.

References : Liu Z. et al.: Eur. J. Med. Chem., 151, 450-461, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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