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ZL-0516

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SI-6128

ZL-0516, >98% (HPLC)

CAS No. : [2230496-93-0]

IUPAC Name : (R)-2-(4-(2-Hydroxy-3-(4-methylpiperazin-1-yl)propoxy)-3,5-dimethylphenyl)-5,7-dimethoxy-4H-chromen-4-one

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C27H34N2O6
Mol. Weight :
482.58
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ZL-0516 functions as a potent and selective inhibitor of the BRD4 BD1 bromodomain with oral activity. It attenuates BRD4/NF‑κB–driven inflammatory responses and demonstrates efficacy in models of inflammatory bowel disease.

References : Ma Z. et al.: ACS Pharmacol. Transl. Sci., 8(4), 1152-1167, 2025; Lu J. et al.: J. Med. Chem., 68(7), 7082-7105, 2025.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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