ZLD-115

SI-8171

ZLD-115, >98% (HPLC)

CAS No. : [2980653-93-6]

IUPAC Name : 2-((1,4-Oxazepan-4-yl)methyl)-6-((2-chloro-6-cyclopropyl-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)benzoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : ZLD115 is an FB23‑derived inhibitor of the RNA demethylase FTO, a key epitranscriptomic regulator implicated in leukemogenesis. By blocking FTO‑mediated m⁶A demethylation, ZLD115 exerts antileukemic activity, showing clear antiproliferative effects across multiple leukemic cell lines. This profile supports its use as a tool compound for studying FTO‑driven AML biology and as a promising lead for FTO‑targeted leukemia therapeutics.

References : Xiao P. et al.: J. Med. Chem., 66(14), 9731-9752, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.