ZN-c5

SI-8088

ZN-c5, >98% (HPLC)

CAS No. : [2136606-87-4]

IUPAC Name : (E)-3-(4-((1R,3R)-2-(Bicyclo[1.1.1]pentan-1-yl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-3,5-difluorophenyl)acrylic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : ZN‑c5 is an orally active SERD with strong potency in ER⁺ breast cancer cells (MCF‑7 IC₅₀ = 0.3 nM) and high affinity for ERα and ERβ. It effectively suppresses tumor growth in MCF‑7 and WHIM20 xenograft models, making it a valuable tool for investigating ER‑dependent breast cancer biology.

References : Hegde S. G. et al.: J. Med. Chem., 68(14), 14740-14755, 2025.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.