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Zoligratinib

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SI-8131

Zoligratinib, >98% (HPLC)

CAS No. : [1265229-25-1]

Synonyms : CH-5183284; Debio-1347

IUPAC Name : (5-Amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone

Price And Availability
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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
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500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C20H16N6O
Mol. Weight :
356.39
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Zoligratinib is a selective oral FGFR inhibitor with low‑nanomolar activity across FGFR1–4 (IC50 = 9.3/7.6/22/22 nM). It is suitable for probing FGFR‑dependent pathways and cancer models.

References : Nakanishi Y. et al.: Mol. Cancer Ther., 13(11), 2547-58, 2014; Nakanishi Y. et al.: Mol. Cancer Ther., 14(3), 704-12, 2015; Nakanishi Y. et al.: Mol. Cancer Ther., 14(12), 2831-9, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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