Zotiraciclib dihydrochloride

SI-7420

Zotiraciclib dihydrochloride, >98% (HPLC)

CAS No. : [1354567-82-0]

Synonyms : TG-02 dihydrochloride

IUPAC Name : (E)-6-Methyl-12-oxa-3,6-diaza-2(4,2)-pyrimidina-1,4(1,3)-dibenzenacyclododecaphan-8-ene dihydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Zotiraciclib dihydrochloride inhibits multiple oncogenic kinases and suppresses tumor growth by lowering Myc levels via CDK9 inhibition. Its pharmacological profile suggests potential activity against tumors capable of penetrating the blood–brain barrier. The compound is associated with elevated MCL‑1 protein levels, highlighting MCL‑1 as a possible survival factor and a candidate target for future mechanistic studies.

References : William A. D. et al.: J. Med. Chem., 55(1), 169-96, 2012; Pasha M. K. et al.: Drug Metab. Lett., 6(1), 33-42, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.