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CAS No. : [1354567-82-0]
IUPAC Name : (E)-6-Methyl-12-oxa-3,6-diaza-2(4,2)-pyrimidina-1,4(1,3)-dibenzenacyclododecaphan-8-ene dihydrochloride
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C23H24N4O • 2HCl | Mol. Weight : 445.39 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Zotiraciclib hydrochloride potently inhibits CDK9, resulting in Myc depletion and suppression of tumor cell growth. It shows promise for treating cancers with central nervous system involvement. Its association with elevated MCL‑1 levels highlights a possible prognostic role and supports continued investigation of MCL‑1–directed therapeutic strategies.
References : William A. D. et al.: J. Med. Chem., 55(1), 169-196, 2012; Pasha M. K. et al.: Drug Metab. Lett., 6(1), 33-42, 2012.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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