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SI-3125

CHMFL-KIT-8140, >98% (HPLC)

Synonyms : N-((1-(4-(3-(3-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG680.00 Back Order Estimated to Ship on 06.12.2024
10MG1280.00 Back Order Estimated to Ship on 06.12.2024
Chemical Properties
C34H36F3N5O5 651.68
White solid Not available
DMSO
For Laboratory research use only, not for drug, household or other uses.
Applications : CHMFL-KIT-8140 is a highly potent type II cKIT kinase inhibitor, which potently inhibited both cKIT wt (IC50 = 33 nM) and cKIT gatekeeper T670I mutant (IC50 = 99 nM). A new potential therapeutic candidate for gastrointestinal stromal tumors.
References : Li B. et al.: J. Med. Chem., 59(18), 8456-8472, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-3125

Product Name : CHMFL-KIT-8140

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