SynInnova Laboratories Inc.

SI-4564

Ponatinib, >98% (HPLC)

CAS No. :

[943319-70-8]

MDL No. :

MFCD17215203

Synonyms : 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide; AP24534

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	90.00	- +	Back Order	Estimated to Ship on 05.31.2024
25MG	180.00	- +	Back Order	Estimated to Ship on 05.31.2024
50MG	350.00	- +	Back Order	Estimated to Ship on 05.31.2024
100MG	650.00	- +	Back Order	Estimated to Ship on 05.31.2024

Chemical Properties
Mol. Formula : C₂₉H₂₇F₃N₆O	Mol. Weight : 532.56
Appearance : Pale yellow solid	Melting Point : Not available
Solubility : DMSO, MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Ponatinib is a potent, orally available multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.

References : O'Hare T. et al.: Cancer Cell,16(5), 401-412, 2009; Gozgit J. M. et al.: Mol Cancer Ther.,10(6), 1028-1035, 2011; Uchida T. et al.: Exp Hematol. 42(5), 369-379, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-4564

Product Name : Ponatinib

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-4564

Ponatinib, >98% (HPLC)

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