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SI-4589

(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine hydrochloride, 97%

CAS No. : 
[1062580-52-2]    

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
1G380.00 Back Order Estimated to Ship on 06.11.2024
5G1380.00 Back Order Estimated to Ship on 06.11.2024
Chemical Properties
C14H22N2 . HCl 291.26
Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an advanced key intermediate in the preparation of Tofacitinib and related analogs, which is a potent, specific, orally active JAK3 inhibitor, used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and ulcerative colitis.
References : Changelian P.S. et al.: Science, 302, (5646), 875-888, 2003; Jiang J. K. et al.: J. Med. Chem., 51(24), 8012-8018, 2008; Kudlacz E. et al.: Am. J. Transplant., 4(1) 51-57, 2004.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-4589

Product Name : (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine hydrochloride

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