SynInnova Laboratories Inc.

SI-4883

Tozasertib, >98% (HPLC)

CAS No. :

[639089-54-6]

MDL No. :

MFCD13185152

Synonyms : N-(4-((4-((5-Methyl-1H-pyrazol-3-yl)amino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl)thio)phenyl)cyclopropanecarboxamide; MK-0457, VX-680

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 06.16.2024
25MG	Request Quote	- +	Back Order	Estimated to Ship on 06.16.2024
100MG	Request Quote	- +	Back Order	Estimated to Ship on 06.16.2024

Chemical Properties
Mol. Formula : C₂₃H₂₈N₈OS	Mol. Weight : 464.59
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Tozasertib is a pan-aurora inhibitor, mostly against aurora A with Kiapp of 0.6 nM in a cell-free assay, less potent towards aurora B/aurora C and 100-fold more selective for aurora A than 55 other kinases.

References : Harrington E. A. et al.: Nat Med.,10(3), 262-267, 2004; Arlot-Bonnemains Y. et al.: Endocr Relat Cancer., 15(2), 559-568, 2008; Young M.A. et al.: Cancer Res., 66(2), 1007-1014, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-4883

Product Name : Tozasertib

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Tozasertib, >98% (HPLC)

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