SynInnova Laboratories Inc.

SI-5103

PQR-530, >98% (HPLC)

CAS No. :

[1927857-61-1]

Synonyms : (S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	180.00	- +	Back Order	Estimated to Ship on 06.06.2024
10MG	280.00	- +	Back Order	Estimated to Ship on 06.06.2024
25MG	500.00	- +	Back Order	Estimated to Ship on 06.06.2024
50MG	750.00	- +	Back Order	Estimated to Ship on 06.06.2024
100MG	1150.00	- +	Back Order	Estimated to Ship on 06.06.2024

Chemical Properties
Mol. Formula : C₁₈H₂₃F₂N₇O₂	Mol. Weight : 407.43
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PQR-530 is a potent, ATP-competitive, orally bioavailable and brain-penetrant dual pan-PI3K/mTORC1/2 inhibitor, with a subnanomolar Kd toward PI3Kα and mTOR (0.84 and 0.33 nM, respectively). PQR-530 is a clinical candidate for the development of therapeutic agent in oncology.

References : Rageot D. et al.: Cancer Res., 77(13 Suppl), 2017; Rageot D. et al.: J. Med Chem., 62(13), 6241-6261, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5103

Product Name : PQR-530

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SI-5103

PQR-530, >98% (HPLC)

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