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SI-5373

Itacitinib adipate, >98% (HPLC)

CAS No. : 
[1334302-63-4]    
Synonyms : 3-(3-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(1-(3-fluoro-2-(trifluoromethyl)isonicotinoyl)piperidin-4-yl)azetidine-3-carbonitrile adipate

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG200.00 Back Order Estimated to Ship on 05.26.2024
25MG350.00 Back Order Estimated to Ship on 05.26.2024
50MG600.00 Back Order Estimated to Ship on 05.26.2024
100MG950.00 Back Order Estimated to Ship on 05.26.2024
250MG1850.00 Back Order Estimated to Ship on 05.26.2024
Chemical Properties
C25H21F4N9O . C6H10O4 685.64
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Itacitinib adipate is an orally active and selective inhibitor of JAK1 with an IC50 of 2 nM for human JAK1. Itacitinib shows >20-fold selectivity for JAK1 over JAK2 and >100-fold over JAK3 and TYK2; Itacitinib is used in the research of myelofibrosis.
References : Mascarenhas J. O. et al.: Haematologica., 102(2), 327-335, 2017; Lescoat A. et al.: Biochem Pharmacol., 178, 114103, 2020.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5373

Product Name : Itacitinib adipate

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